Use of the MS-MLPA assay in prenatal diagnosis of Prader–Willi syndrome with mosaic trisomy 15

Use of the MS-MLPA assay in prenatal diagnosis of Prader–Willi syndrome with mosaic trisomy 15

Objective: We present a prenatal diagnosis strategy of using Methylation-Specific Multiplex Ligation-Dependent Probe Amplification (MS-MLPA) for the detection of maternal uniparental disomy 15/trisomy 15 (UPD(15) mat/T15) mosaicism. Case report: A 43-year-old woman underwent amniocentesis at 19 week...

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Bibliographic Details
Main Authors: Meizi Zhang, Yuehong Liang, Hui Li, Fengqin Xu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Amniocentesis
Maternal uniparental disomy 15
Mosaic trisomy 15
Prader–Willi syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455923003091

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http://www.sciencedirect.com/science/article/pii/S1028455923003091

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