A Novel Class of Dual-Acting DCH-CORMs Counteracts Oxidative Stress-Induced Inflammation in Human Primary Tenocytes

A Novel Class of Dual-Acting DCH-CORMs Counteracts Oxidative Stress-Induced Inflammation in Human Primary Tenocytes

Carbon monoxide (CO) can prevent cell and tissue damage by restoring redox homeostasis and counteracting inflammation. CO-releasing molecules (CORMs) can release a controlled amount of CO to cells and are emerging as a safer therapeutic alternative to delivery of CO in vivo. Sustained oxidative stre...

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Bibliographic Details
Main Authors: Federico Appetecchia, Sara Consalvi, Emanuela Berrino, Marialucia Gallorini, Arianna Granese, Cristina Campestre, Simone Carradori, Mariangela Biava, Giovanna Poce
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antioxidants
Subjects:
CO-releasing molecules
tenocytes
PGE<sub>2</sub>
1,5-diarylpyrrole
1,5-diarylpyrazole
carbon monoxide
Online Access:https://www.mdpi.com/2076-3921/10/11/1828

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https://www.mdpi.com/2076-3921/10/11/1828

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