Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of Legionella pneumophila

Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of Legionella pneumophila

ABSTRACT Toxin-antitoxin (TA) systems are abundant genetic modules in bacterial chromosomes and on mobile elements. They are often patchily distributed, as a consequence of horizontal exchange, and the breadth of their functionality in bacterial physiology remains unknown. Here, we characterize a TA...

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Bibliographic Details
Main Authors: Jordan D. Lin, Peter J. Stogios, Kento T. Abe, Avril Wang, John MacPherson, Tatiana Skarina, Anne-Claude Gingras, Alexei Savchenko, Alexander W. Ensminger
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Legionella pneumophila
toxin-antitoxin system
HipBA
HipBST
split hipA
kinase
Online Access:https://journals.asm.org/doi/10.1128/mbio.01510-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01510-23

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