Sequence and structural conservation reveal fingerprint residues in TRP channels

Sequence and structural conservation reveal fingerprint residues in TRP channels

Transient receptor potential (TRP) proteins are a large family of cation-selective channels, surpassed in variety only by voltage-gated potassium channels. Detailed molecular mechanisms governing how membrane voltage, ligand binding, or temperature can induce conformational changes promoting the ope...

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Bibliographic Details
Main Authors: Deny Cabezas-Bratesco, Francisco A Mcgee, Charlotte K Colenso, Kattina Zavala, Daniele Granata, Vincenzo Carnevale, Juan C Opazo, Sebastian E Brauchi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
evolution
MSA
allosterism
structure
TRP channels
Online Access:https://elifesciences.org/articles/73645

Internet

https://elifesciences.org/articles/73645

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