Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells

Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells

Light-inducible dimerization protein modules enable precise temporal and spatial control of biological processes in non-invasive fashion. Among them, Magnets are small modules engineered from the Neurospora crassa photoreceptor Vivid by orthogonalizing the homodimerization interface into complementa...

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Bibliographic Details
Main Authors: Lorena Benedetti, Jonathan S Marvin, Hanieh Falahati, Andres Guillén-Samander, Loren L Looger, Pietro De Camilli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
LOV domain
light-dependent dimerizers
organelle contacts
VAP
contact sites
Vivid
Online Access:https://elifesciences.org/articles/63230

Internet

https://elifesciences.org/articles/63230

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