Hepatitis E genotype 3 genome: A comprehensive analysis of entropy, motif conservation, relevant mutations, and clade-associated polymorphisms

Hepatitis E genotype 3 genome: A comprehensive analysis of entropy, motif conservation, relevant mutations, and clade-associated polymorphisms

Hepatitis E virus genotype 3 (HEV-3) is an EU/EEA emergent zoonosis. HEV-3 clades/subtypes have been described. Its genome contains ORF1, which encodes nonstructural proteins for virus replication, ORF2, the capsid protein, and ORF3, a multifunctional protein involved in virion pathogenesis. The stu...

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Bibliographic Details
Main Authors: Milagros Muñoz-Chimeno, Vanessa Rodriguez-Paredes, Maira Alejandra García-Lugo, Ana Avellon
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Microbiology
Subjects:
hepatitis E virus
HEV
domains
polymorphisms
entropy
genome
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1011662/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1011662/full

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