Endoplasmic reticulum chaperones and their roles in the immunogenicity of cancer vaccines

The endoplasmic reticulum (ER) is a major site of passage for proteins en route to other organelles, to the cell surface, and to the extracellular space. It is also the transport route for peptides generated in the cytosol by the proteasome into the ER for loading onto major histocompatibility compl...

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Bibliographic Details
Main Authors: Michael William Graner, Kevin O Lillehei, Emmanuel eKatsanis
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00379/full