UBE2S promotes the development of ovarian cancer by promoting PI3K/AKT/mTOR signaling pathway to regulate cell cycle and apoptosis

UBE2S promotes the development of ovarian cancer by promoting PI3K/AKT/mTOR signaling pathway to regulate cell cycle and apoptosis

Abstract Background Ovarian cancer is one of the important factors that seriously threaten women's health and its morbidity and mortality ranks eighth among female cancers in the world. It is critical to identify potential and promising biomarkers for prognostic evaluation and molecular therapy...

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Bibliographic Details
Main Authors: Mengjun Zhang, Yuan Liu, Yue Yin, Zhenxing Sun, Yan Wang, Zexue Zhang, Fei Li, Xiuwei Chen
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Medicine
Subjects:
Ovarian cancer
Ubiquitin-conjugating enzyme E2S
Prognosis
Malignant biological behavior
Cell cycle
Apoptosis
Online Access:https://doi.org/10.1186/s10020-022-00489-2

Internet

https://doi.org/10.1186/s10020-022-00489-2

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