Impact of Inosine on Chronic Unpredictable Mild Stress-Induced Depressive and Anxiety-Like Behaviors With the Alteration of Gut Microbiota

Impact of Inosine on Chronic Unpredictable Mild Stress-Induced Depressive and Anxiety-Like Behaviors With the Alteration of Gut Microbiota

Current antidepressants do not confer a clear advantage in children and adolescents with major depressive disorder (MDD). Accumulating evidence highlights the potential antidepressant-like effects of inosine on adult MDD, and gut microbiomes are significantly associated with MDD via the microbiota-g...

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Bibliographic Details
Main Authors: Xueer Liu, Teng Teng, Xuemei Li, Li Fan, Yajie Xiang, Yuanliang Jiang, Kang Du, Yuqing Zhang, Xinyu Zhou, Peng Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
depression
inosine
gut microbiota
chronic unpredictable mild stress
adolescent mice
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.697640/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.697640/full

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