Burn and thoracic trauma alters fracture healing, systemic inflammation, and leukocyte kinetics in a rat model of polytrauma

Abstract Background Singular traumatic insults, such as bone fracture, typically initiate an appropriate immune response necessary to restore the host to pre-insult homeostasis with limited damage to self. However, multiple concurrent insults, such as a combination of fracture, blunt force trauma, a...

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Bibliographic Details
Main Authors: Lauren H. Mangum, Joshua J. Avila, Brady J. Hurtgen, Alicia L. Lofgren, Joseph C. Wenke
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13018-019-1082-4