m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs

m6A regulation of cortical and retinal neurogenesis is mediated by the redundant m6A readers YTHDFs

Summary: m6A modification plays an important role in regulating mammalian neurogenesis. However, whether and how the major cytoplasmic m6A readers, YTHDF1, YTHDF2, and YTHDF3 mediate this process is still not clear. Here, we demonstrate that Ythdf1 and Ythdf2 double deletion but not individual knock...

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Bibliographic Details
Main Authors: Fugui Niu, Pengfei Che, Zhuoxuan Yang, Jian Zhang, Lixin Yang, Mengru Zhuang, Xijun Ou, Sheng-Jian Ji
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:iScience
Subjects:
Molecular biology
Molecular Genetics
Neuroscience
Molecular neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222011804

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http://www.sciencedirect.com/science/article/pii/S2589004222011804

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