An Integrative Approach to Computational Modelling of the Gene Regulatory Network Controlling Clostridium botulinum Type A1 Toxin Production.

Clostridium botulinum produces botulinum neurotoxins (BoNTs), highly potent substances responsible for botulism. Currently, mathematical models of C. botulinum growth and toxigenesis are largely aimed at risk assessment and do not include explicit genetic information beyond group level but integrate...

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Bibliographic Details
Main Authors: Adaoha E C Ihekwaba, Ivan Mura, John Walshaw, Michael W Peck, Gary C Barker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5113860?pdf=render