Immune niches orchestrated by intestinal mesenchymal stromal cells lining the crypt-villus

The mammalian intestine is an organ that can be spatially defined by two axes: longitudinal and vertical. Such anatomical structure ensures the maintenance of a relatively immuno-quiescent and proliferation-promoting crypt for intestinal stem cell differentiation while actively warding off the invad...

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Bibliographic Details
Main Authors: Hongxiang Sun, Jianmei Tan, Hongqian Chen, Ningbo Wu, Bing Su
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1057932/full