The iron–sulfur‐containing HypC‐HypD scaffold complex of the [NiFe]‐hydrogenase maturation machinery is an ATPase

HypD and HypC, or its paralogue HybG in Escherichia coli, form the core of the scaffold complex that synthesizes the Fe(CN)2CO component of the bimetallic NiFe‐cofactor of [NiFe]‐hydrogenase. We show here that purified HypC‐HypD and HybG‐HypD complexes catalyse hydrolysis of ATP to ADP (kcat ≅ 0.85·...

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Bibliographic Details
Main Authors: Kerstin Nutschan, Ralph P. Golbik, R. Gary Sawers
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12743