The Relationship between the IC<sub>50</sub> Values and the Apparent Inhibition Constant in the Study of Inhibitors of Tyrosinase Diphenolase Activity Helps Confirm the Mechanism of Inhibition

The Relationship between the IC<sub>50</sub> Values and the Apparent Inhibition Constant in the Study of Inhibitors of Tyrosinase Diphenolase Activity Helps Confirm the Mechanism of Inhibition

Tyrosinase is the enzyme involved in melanization and is also responsible for the browning of fruits and vegetables. Control of its activity can be carried out using inhibitors, which is interesting in terms of quantitatively understanding the action of these regulators. In the study of the inhibiti...

Full description

Bibliographic Details
Main Authors: Pablo Garcia-Molina, Francisco Garcia-Molina, Jose Antonio Teruel-Puche, Jose Neptuno Rodriguez-Lopez, Francisco Garcia-Canovas, Jose Luis Muñoz-Muñoz
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
tyrosinase
polyphenol oxidase
diphenolase activity
IC<sub>50</sub>
inhibition
<named-content content-type="equation"><inline-formula> <mml:math id="mm400"> <mml:semantics> <mml:mrow> <mml:msubsup> <mml:mi mathvariant="normal">K</mml:mi> <mml:mi mathvariant="normal">I</mml:mi> <mml:mrow> <mml:mi>app</mml:mi> </mml:mrow> </mml:msubsup> </mml:mrow> </mml:semantics> </mml:math> </inline-formula></named-content>
Online Access:https://www.mdpi.com/1420-3049/27/10/3141

Internet

https://www.mdpi.com/1420-3049/27/10/3141

Similar Items