NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions

NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions

Preeclampsia (PE) is a specific syndrome of human pregnancy, being one of the main causes of maternal death. Persistent inflammation in the endothelium stimulates the secretion of several inflammatory mediators, activating different signaling patterns. One of these mechanisms is related to NLRP3 act...

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Bibliographic Details
Main Authors: Priscila Rezeck Nunes, Sarah Viana Mattioli, Valeria Cristina Sandrim
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cells
Subjects:
NLRP3
preeclampsia
nitric oxide
endothelial dysfunction
oxidative stress
inflammation
Online Access:https://www.mdpi.com/2073-4409/10/11/2828

Internet

https://www.mdpi.com/2073-4409/10/11/2828

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