Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology

Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology

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The p38 alpha mitogen-activated protein kinase (p38α) is linked to both innate and adaptive immune responses and is under investigation as a target for drug development in the context of Alzheimer’s disease (AD) and other conditions with neuroinflammatory dysfunction. While preclinical data has show...

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Bibliographic Details
Main Authors: David J. Braun, Hilaree N. Frazier, Verda A. Davis, Meggie J. Coleman, Colin B. Rogers, Linda J. Van Eldik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231773/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10231773/?tool=EBI

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