The effects of amino acid substitution of spike protein and genomic recombination on the evolution of SARS-CoV-2

Over three years’ pandemic of 2019 novel coronavirus disease (COVID-19), multiple variants and novel subvariants have emerged successively, outcompeted earlier variants and become predominant. The sequential emergence of variants reflects the evolutionary process of mutation-selection-adaption of se...

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Bibliographic Details
Main Authors: Letian Fang, Jie Xu, Yue Zhao, Junyan Fan, Jiaying Shen, Wenbin Liu, Guangwen Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1228128/full