Potent Activation of Human but Not Mouse TRPA1 by JT010
Transient receptor potential (TRP) ankyrin repeat 1 (TRPA1), which is involved in inflammatory pain sensation, is activated by endogenous factors, such as intracellular Zn<sup>2+</sup> and hydrogen peroxide, and by irritant chemical compounds. The synthetic compound JT010 potently and se...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/22/14297 |