Potent Activation of Human but Not Mouse TRPA1 by JT010

Potent Activation of Human but Not Mouse TRPA1 by JT010

Transient receptor potential (TRP) ankyrin repeat 1 (TRPA1), which is involved in inflammatory pain sensation, is activated by endogenous factors, such as intracellular Zn<sup>2+</sup> and hydrogen peroxide, and by irritant chemical compounds. The synthetic compound JT010 potently and se...

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Bibliographic Details
Main Authors:	Masaki Matsubara, Yukiko Muraki, Noriyuki Hatano, Hiroka Suzuki, Katsuhiko Muraki
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	International Journal of Molecular Sciences
Subjects:	JT010 calcium channel transient receptor potential ankyrin repeat 1 synoviocytes dorsal root ganglion
Online Access:	https://www.mdpi.com/1422-0067/23/22/14297

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