Five Withanolides from the Leaves of Datura metel L. and Their Inhibitory Effects on Nitric Oxide Production

Five Withanolides from the Leaves of Datura metel L. and Their Inhibitory Effects on Nitric Oxide Production

Four new withanolides named dmetelins A–D (compounds 1–4), along with the known compound 7α,27-dihydroxy-1-oxo-witha-2,5,24-trienolide (5) were isolated from the leaves of Datura metel L. (Solanaceae). Their structures were elucidated on the basis of detailed analysis of 1D and 2D NMR and mass spect...

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Bibliographic Details
Main Authors: Bing-You Yang, Rui Guo, Ting Li, Yan Liu, Chang-Fu Wang, Zun-Peng Shu, Zhi-Bin Wang, Jing Zhang, Yong-Gang Xia, Hai Jiang, Qiu-Hong Wang, Hai-Xue Kuang
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
Datura metel L.
withanolides
dmetelins
NO inhibition
Online Access:http://www.mdpi.com/1420-3049/19/4/4548

Internet

http://www.mdpi.com/1420-3049/19/4/4548

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