New Mutations in cls Lead to Daptomycin Resistance in a Clinical Vancomycin- and Daptomycin-Resistant Enterococcus faecium Strain

New Mutations in cls Lead to Daptomycin Resistance in a Clinical Vancomycin- and Daptomycin-Resistant Enterococcus faecium Strain

Daptomycin (DAP), a last-resort antibiotic for treating Gram-positive bacterial infection, has been widely used in the treatment of vancomycin-resistant enterococci (VRE). Resistance to both daptomycin and vancomycin leads to difficulties in controlling infections of enterococci. A clinical multidru...

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Bibliographic Details
Main Authors: Weiwei Li, Jiamin Hu, Ling Li, Mengge Zhang, Qingyu Cui, Yanan Ma, Hainan Su, Xuhua Zhang, Hai Xu, Mingyu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
vancomycin-resistant enterococci
Enterococcus faecium
daptomycin resistance
vancomycin resistance
membrane surface charge
gdpD
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.896916/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.896916/full

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