Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against Cryptococcus neoformans

Antifungal activity of eumelanin-inspired indoylenepheyleneethynylene against Cryptococcus neoformans

Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningitis in >152,000 immunocompromised individuals annually, leading to 112,000 yearly deaths. The four classes of existing antifungal agents target plasma membrane sterols (ergosterol), nucleic acid synthesis, and cell...

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Bibliographic Details
Main Authors: Brittney N. Conn, Jacob A. Lieberman, Priscilla Chatman, Kaitlyn Cotton, Martha A. Essandoh, Mohammad Ebqa’ai, Toby L. Nelson, Karen L. Wozniak
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
Cryptococcus neoformans
antifungal
novel antifungal compound
EIPE-1
eumelanin
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1339303/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1339303/full

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