Functional consequences of mitochondrial mismatch in reconstituted embryos and offspring

Animal cloning technology has been developed to produce progenies genetically identical to a given donor cell. However, in nuclear transfer protocols, the recipient oocytes contribute a heritable mitochondrial genomic (mtDNA) background to the progeny. Additionally, a small amount of donor cell-deri...

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Bibliographic Details
Main Author: Kumiko TAKEDA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2019-08-01
Series:The Journal of Reproduction and Development
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jrd/65/6/65_2019-089/_pdf/-char/en