GenoMine: a CRISPR-Cas9-based kill switch for biocontainment of Pseudomonas putida

GenoMine: a CRISPR-Cas9-based kill switch for biocontainment of Pseudomonas putida

Synthetic genetic circuits have revolutionised our capacity to control cell viability by conferring microorganisms with programmable functionalities to limit survival to specific environmental conditions. Here, we present the GenoMine safeguard, a CRISPR-Cas9-based kill switch for the biotechnologic...

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Bibliographic Details
Main Authors: Enrique Asin-Garcia, Maria Martin-Pascual, Claudia de Buck, Max Allewijn, Alexandra Müller, Vitor A. P. Martins dos Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
CRISPR-Cas9-mediated biocontainment
kill switch
riboregulator
genetic circuit
P. putida
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2024.1426107/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2024.1426107/full

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