Antidepressant Effect of Intermittent Long-Term Systemic Administration of Irisin in Mice

Antidepressant Effect of Intermittent Long-Term Systemic Administration of Irisin in Mice

Depression is a psychiatric disorder increasingly diffused worldwide. Evidence suggests that irisin, a myokine secreted by contracting muscle, mediates beneficial effects on several targets, including the brain. Here, the potential antidepressant properties of long-term intermittent systemic irisin...

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Bibliographic Details
Main Authors: Patrizia Pignataro, Manuela Dicarlo, Roberta Zerlotin, Giuseppina Storlino, Angela Oranger, Lorenzo Sanesi, Roberto Lovero, Cinzia Buccoliero, Giorgio Mori, Graziana Colaianni, Silvia Colucci, Maria Grano
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:International Journal of Molecular Sciences
Subjects:
depression
antidepressant
irisin
FNDC5
physical exercise
open field test
Online Access:https://www.mdpi.com/1422-0067/23/14/7596

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https://www.mdpi.com/1422-0067/23/14/7596

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