An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV

An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoV

ABSTRACTThe capacity of SARS-CoV-2 to evolve poses challenges to conventional prevention and treatment options such as vaccination and monoclonal antibodies, as they rely on viral receptor binding domain (RBD) sequences from previous strains. Additionally, animal CoVs, especially those of the SARS f...

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Bibliographic Details
Main Authors: Hailong Guo, Bomsoo Cho, Paul R. Hinton, Sijia He, Yongjun Yu, Ashwin Kumar Ramesh, Jwala Priyadarsini Sivaccumar, Zhiqiang Ku, Kristen Campo, Sarah Holland, Sameer Sachdeva, Christopher Mensch, Mohamed Dawod, Annalis Whitaker, Philip Eisenhauer, Allison Falcone, Rebekah Honce, Jason W. Botten, Stephen F. Carroll, Bruce A. Keyt, Andrew W. Womack, William R. Strohl, Kai Xu, Ningyan Zhang, Zhiqiang An, Sha Ha, John W. Shiver, Tong-Ming Fu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV
ACE2 viral trap
neutralization
viral challenge
inhalation
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2023.2275598

Internet

https://www.tandfonline.com/doi/10.1080/22221751.2023.2275598

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