Antileishmanial Activity, Toxicity and Mechanism of Action of Complexes of Sodium Usnate with Lanthanide Ions: Eu(III), Sm(III), Gd(III), Nd(III), La(III) and Tb(III)

Antileishmanial Activity, Toxicity and Mechanism of Action of Complexes of Sodium Usnate with Lanthanide Ions: Eu(III), Sm(III), Gd(III), Nd(III), La(III) and Tb(III)

Leishmaniases are neglected diseases with limited therapeutic options. Diffuse cutaneous leishmaniasis can occur in Brazil due to <i>Leishmania amazonensis</i>. This study details the antileishmanial activity and cytotoxicity of complexes of sodium usnate (SAU) with lanthanide ions ([LnL...

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Bibliographic Details
Main Authors: Fernanda da Silva, Yasmin Silva Rizk, Amarith Rodrigues das Neves, Estela Mariana Guimarães Lourenço, Alda Maria Teixeira Ferreira, Melquisedeque Mateus Monteiro, Dênis Pires de Lima, Renata Trentin Perdomo, Iluska Senna Bonfá, Mônica Cristina Toffoli-Kadri, Adriana Pereira Duarte, Daniel Mendes Nunes, Marco Antonio Utrera Martines, Eliane Mattos Piranda, Carla Cardozo Pinto de Arruda
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
lanthanide complexes
biological activity
<i>Leishmania amazonensis</i>
cytotoxicity
selectivity
mechanism of action
Online Access:https://www.mdpi.com/1422-0067/25/1/413

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https://www.mdpi.com/1422-0067/25/1/413

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