Inhibition of MACC1-Induced Metastasis in Esophageal and Gastric Adenocarcinomas

Inhibition of MACC1-Induced Metastasis in Esophageal and Gastric Adenocarcinomas

Esophageal and Gastric Adenocarcinomas (AGE/S) are characterized by early metastasis and poor survival. MACC1 (Metastasis Associated in Colon Cancer 1) acts in colon cancer as a metastasis inducer and is linked to reduced survival. This project illuminates the role and potential for the inhibition o...

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Bibliographic Details
Main Authors: Christoph Treese, Jessica Werchan, Moritz von Winterfeld, Erika Berg, Michael Hummel, Lena Timm, Beate Rau, Ole Daberkow, Wolfgang Walther, Severin Daum, Dennis Kobelt, Ulrike Stein
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
gastric cancer
esophageal cancer
metastasis
MACC1
MEK1 inhibition
selumetinib
Online Access:https://www.mdpi.com/2072-6694/14/7/1773

Internet

https://www.mdpi.com/2072-6694/14/7/1773

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