A COVID-19 DNA Vaccine Candidate Elicits Broadly Neutralizing Antibodies against Multiple SARS-CoV-2 Variants including the Currently Circulating Omicron BA.5, BF.7, BQ.1 and XBB

A COVID-19 DNA Vaccine Candidate Elicits Broadly Neutralizing Antibodies against Multiple SARS-CoV-2 Variants including the Currently Circulating Omicron BA.5, BF.7, BQ.1 and XBB

Waves of breakthrough infections by SARS-CoV-2 Omicron subvariants currently pose a global challenge to the control of the COVID-19 pandemic. We previously reported a pVAX1-based DNA vaccine candidate, pAD1002, that encodes a receptor-binding domain (RBD) chimera of SARS-CoV-1 and Omicron BA.1. In m...

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Bibliographic Details
Main Authors: Yuan Ding, Feng Fan, Xin Xu, Gan Zhao, Xin Zhang, Huiyun Zhao, Limei Wang, Bin Wang, Xiao-Ming Gao
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Vaccines
Subjects:
COVID-19
SARS-CoV-2
DNA vaccine
RBD chimera
Omicron
Online Access:https://www.mdpi.com/2076-393X/11/4/778

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https://www.mdpi.com/2076-393X/11/4/778

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