Involvement of brain-derived neurotrophic factor (BDNF) in chronic intermittent stress-induced enhanced mechanical allodynia in a rat model of burn pain

Involvement of brain-derived neurotrophic factor (BDNF) in chronic intermittent stress-induced enhanced mechanical allodynia in a rat model of burn pain

Abstract Background Reports show that stressful events before injury exacerbates post-injury pain. The mechanism underlying stress-induced heightened thermal pain is unclear. Here, we examined the effects of chronic intermittent stress (CIS) on nociceptive behaviors and brain-derived nerve growth fa...

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Bibliographic Details
Main Authors: Natasha M. Sosanya, Thomas H. Garza, Winfred Stacey, Stephen L. Crimmins, Robert J. Christy, Bopaiah P. Cheppudira
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Neuroscience
Subjects:
Chronic intermittent stress
Thermal injury
Mechanical allodynia
BDNF
TrkB
p-TrkB
Online Access:http://link.springer.com/article/10.1186/s12868-019-0500-1

Internet

http://link.springer.com/article/10.1186/s12868-019-0500-1

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