Suppressed renoprotective purines in COVID-19 patients with acute kidney injury

Abstract Acute kidney injury (AKI) is common in patients hospitalized for COVID-19, complicating their clinical course and contributing to worse outcomes. Animal studies show that adenosine, inosine and guanosine protect the kidney against some types of AKI. However, until now there was no evidence...

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Bibliographic Details
Main Authors: Edwin K. Jackson, Georgios D. Kitsios, Michael Y. Lu, Caitlin M. Schaefer, Cathy J. Kessinger, Bryan J. McVerry, Alison Morris, Bernard J. C. Macatangay
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22349-z