miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions

Cortical lesions represent a hallmark of multiple sclerosis and are proposed as a predictor of disease severity. microRNAs are suggested to be important players in the disease pathogenesis and the experimental autoimmune encephalomyelitis animal model. We implemented a mouse model recapitulating mor...

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Bibliographic Details
Main Authors: Nicola S Orefice, Owein Guillemot-Legris, Rosanna Capasso, Pauline Bottemanne, Philippe Hantraye, Michele Caraglia, Giuseppe Orefice, Mireille Alhouayek, Giulio G Muccioli
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/56916