Circ-UBR4 regulates the proliferation, migration, inflammation, and apoptosis in ox-LDL-induced vascular smooth muscle cells via miR-515-5p/IGF2 axis

The aim of our study is to disclose the role and underlying molecular mechanisms of circular RNA ubiquitin protein ligase E3 component n-recognin 4 (circ-UBR4) in atherosclerosis (AS). Our data showed that circ-UBR4 expression was upregulated in AS patients and oxidized low-density lipoprotein (ox-L...

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Bibliographic Details
Main Authors: Feng Liuliu, Liu Tianhua, Shi Jun, Wang Yu, Yang Yuya, Xiao Wenyin, Bai Yanyan
Format: Article
Language:English
Published: De Gruyter 2023-08-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2023-0751