Application of Causal Inference to Genomic Analysis: Advances in Methodology

Application of Causal Inference to Genomic Analysis: Advances in Methodology

The current paradigm of genomic studies of complex diseases is association and correlation analysis. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), the identified genetic variants by GWAS can only explain a small pro...

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Bibliographic Details
Main Authors: Pengfei Hu, Rong Jiao, Li Jin, Momiao Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Genetics
Subjects:
causal inference
genomic analysis
additive noise models for discrete variables
association analysis
entropy
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00238/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00238/full

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