Cortical structural changes of morphometric similarity network in early-onset schizophrenia correlate with specific transcriptional expression patterns

Cortical structural changes of morphometric similarity network in early-onset schizophrenia correlate with specific transcriptional expression patterns

Abstract Background This study aimed to investigate the neuroanatomical subtypes among early-onset schizophrenia (EOS) patients by exploring the association between structural alterations and molecular mechanisms using a combined analysis of morphometric similarity network (MSN) changes and specific...

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Bibliographic Details
Main Authors: Guanqun Yao, Ting Zou, Jing Luo, Shuang Hu, Langxiong Yang, Jing Li, Xinrong Li, Yuqi Zhang, Kun Feng, Yong Xu, Pozi Liu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Medicine
Subjects:
Early-onset schizophrenia
Morphometric similarity network
Neuroanatomical subtypes
Transcriptional signatures
Cell type-specific signatures
Online Access:https://doi.org/10.1186/s12916-023-03201-1

Internet

https://doi.org/10.1186/s12916-023-03201-1

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