Critically ill COVID-19 patients with neutralizing autoantibodies against type I interferons have increased risk of herpesvirus disease.

Critically ill COVID-19 patients with neutralizing autoantibodies against type I interferons have increased risk of herpesvirus disease.

Autoantibodies neutralizing the antiviral action of type I interferons (IFNs) have been associated with predisposition to severe Coronavirus Disease 2019 (COVID-19). Here, we screened for such autoantibodies in 103 critically ill COVID-19 patients in a tertiary intensive care unit (ICU) in Switzerla...

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Bibliographic Details
Main Authors: Idoia Busnadiego, Irene A Abela, Pascal M Frey, Daniel A Hofmaenner, Thomas C Scheier, Reto A Schuepbach, Philipp K Buehler, Silvio D Brugger, Benjamin G Hale
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3001709

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https://doi.org/10.1371/journal.pbio.3001709

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