Placental Malaria is Associated with Higher LILRB2 Expression in Monocyte Subsets and Lower Anti-Malarial IgG Antibodies During Infancy

Placental Malaria is Associated with Higher LILRB2 Expression in Monocyte Subsets and Lower Anti-Malarial IgG Antibodies During Infancy

BackgroundPlacental malaria (PM) is associated with a higher susceptibility of infants to Plasmodium falciparum (Pf) malaria. A hypothesis of immune tolerance has been suggested but no clear explanation has been provided so far. Our goal was to investigate the involvement of inhibitory receptors LIL...

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Bibliographic Details
Main Authors: Celia Dechavanne, Odilon Nouatin, Rafiou Adamou, Sofie Edslev, Anita Hansen, Florian Meurisse, Ibrahim Sadissou, Erasme Gbaguidi, Jacqueline Milet, Gilles Cottrell, Laure Gineau, Audrey Sabbagh, Achille Massougbodji, Kabirou Moutairou, Eduardo A. Donadi, Edgardo D. Carosella, Philippe Moreau, Ed Remarque, Michael Theisen, Nathalie Rouas-Freiss, André Garcia, Benoit Favier, David Courtin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
LILRB1
LILRB2
Plasmodium falciparum
immune tolerance
HLA-G
Gd T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.909831/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.909831/full

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