Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice

Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice

Abstract The ventral striatum is a reward center implicated in the pathophysiology of depression. It contains islands of Calleja, clusters of dopamine D3 receptor-expressing granule cells, predominantly in the olfactory tubercle (OT). These OT D3 neurons regulate self-grooming, a repetitive behavior...

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Bibliographic Details
Main Authors: Yun-Feng Zhang, Jialiang Wu, Yingqi Wang, Natalie L. Johnson, Janardhan P. Bhattarai, Guanqing Li, Wenqiang Wang, Camilo Guevara, Hannah Shoenhard, Marc V. Fuccillo, Daniel W. Wesson, Minghong Ma
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42662-z

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https://doi.org/10.1038/s41467-023-42662-z

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