Towards predictive computational models of oncolytic virus therapy: basis for experimental validation and model selection.

Oncolytic viruses are viruses that specifically infect cancer cells and kill them, while leaving healthy cells largely intact. Their ability to spread through the tumor makes them an attractive therapy approach. While promising results have been observed in clinical trials, solid success remains elu...

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Bibliographic Details
Main Authors: Dominik Wodarz, Natalia Komarova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2629569?pdf=render