Towards predictive computational models of oncolytic virus therapy: basis for experimental validation and model selection.

Oncolytic viruses are viruses that specifically infect cancer cells and kill them, while leaving healthy cells largely intact. Their ability to spread through the tumor makes them an attractive therapy approach. While promising results have been observed in clinical trials, solid success remains elu...

Полное описание

Библиографические подробности
Главные авторы: Dominik Wodarz, Natalia Komarova
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2009-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC2629569?pdf=render