Macrophage metabolism, phenotype, function, and therapy in hepatocellular carcinoma (HCC)

Abstract The pivotal role of the tumor microenvironment (TME) in the initiation and advancement of hepatocellular carcinoma (HCC) is widely acknowledged, as it fosters the proliferation and metastasis of HCC cells. Within the intricate TME of HCC, tumor-associated macrophages (TAMs) represent a sign...

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Bibliographic Details
Main Authors: Jingquan Huang, Qiulin Wu, David A. Geller, Yihe Yan
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-023-04716-0