High-Voltage Electrostatic Field Hydrogel Microsphere 3D Culture System Improves Viability and Liver-like Properties of HepG2 Cells

High-Voltage Electrostatic Field Hydrogel Microsphere 3D Culture System Improves Viability and Liver-like Properties of HepG2 Cells

Three-dimensional (3D) hepatocyte models have become a research hotspot for evaluating drug metabolism and hepatotoxicity. Compared to two-dimensional (2D) cultures, 3D cultures are better at mimicking the morphology and microenvironment of hepatocytes in vivo. However, commonly used 3D culture tech...

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Bibliographic Details
Main Authors: Yi Liu, Yang Ge, Yanfan Wu, Yongtong Feng, Han Liu, Wei Cao, Jinsong Xie, Jingzhong Zhang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocyte
3D cultures
hydrogel
microspheres
high-voltage electrostatic field
RNA-seq
Online Access:https://www.mdpi.com/1422-0067/25/2/1081

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https://www.mdpi.com/1422-0067/25/2/1081

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