Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair

Constitutive heterochromatin is considered as a functionally inert genome compartment, important for its architecture and stability. How such stable structure is maintained is not well understood. Here, we apply four different visualization schemes to label it and investigate its dynamics during DNA...

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Bibliographic Details
Main Authors: Vadim O. Chagin, Britta Reinhart, Annette Becker, Oliver Mortusewicz, K. Laurence Jost, Alexander Rapp, Heinrich Leonhardt, M. Cristina Cardoso
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Nucleus
Subjects:
Online Access:http://dx.doi.org/10.1080/19491034.2019.1688932