Gold nanoparticles loaded chitosan encapsulate 6-mercaptopurine as a novel nanocomposite for chemo-photothermal therapy on breast cancer

Abstract Background As a promising strategy to overcome the therapeutic disadvantages of 6-mercaptopurine (6MP), we proposed the encapsulation of 6MP in chitosan nanoparticles (CNPs) to form the 6MP-CNPs complexes. The encapsulation was followed by the loading of complexes on gold nanoparticles (AuN...

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Bibliographic Details
Main Authors: Amna H. Faid, Samia A. Shouman, Yehia A. Badr, Marwa Sharaky, Elham M. Mostafa, Mahmoud A. Sliem
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Chemistry
Subjects:
Online Access:https://doi.org/10.1186/s13065-022-00892-0