Effects of dehydroepiandrosterone alone or in combination with a high-fat diet and antibiotic cocktail on the heterogeneous phenotypes of PCOS mouse models by regulating gut microbiota

Effects of dehydroepiandrosterone alone or in combination with a high-fat diet and antibiotic cocktail on the heterogeneous phenotypes of PCOS mouse models by regulating gut microbiota

ObjectivePolycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disease. The gut microbiota is highly correlated with androgen secretion and insulin resistance (IR), which are two potential major pathogenic mechanisms of PCOS. Currently, an antibiotic cocktail (ABX) is often use...

Full description

Bibliographic Details
Main Authors: Xuejiao Wang, Liping Gu, Yahui Zhang, Chuanhao Xiong, Yongde Peng, Xiaoying Ding
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
polycystic ovary syndrome
mouse model
phenotype
dehydroepiandrosterone
high-fat diet
antibiotic cocktail
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1030151/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1030151/full

Similar Items