Association between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease

Association between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease

IntroductionChagas disease causes a cardiac illness characterized by immunoinflammatory reactions leading to myocardial fibrosis and remodeling. The development of Chronic Chagas Cardiomyopathy (CCC) in some patients while others remain asymptomatic is not fully understood, but dysregulated inflamma...

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Main Authors: Laura Fernanda Ambrosio, Ximena Volpini, Juan Nahuel Quiroz, María Belén Brugo, Carolina Paola Knubel, Melisa Rocío Herrera, Laura Fozzatti, Julián Avila Pacheco, Clary B. Clish, Maisa C. Takenaka, Juan Beloscar, Martín Gustavo Theumer, Francisco Javier Quintana, Ana Rosa Perez, Claudia Cristina Motrán
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
Chagas
AhR
tryptophan
IDO
T. cruzi
metabolomic
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267641/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1267641/full

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