Localization of drug biodistribution in a 3D-bioengineered subcutaneous neovascularized microenvironment

Localization of drug biodistribution in a 3D-bioengineered subcutaneous neovascularized microenvironment

Local immunomodulation has shown the potential to control the immune response in a site-specific manner for wound healing, cancer, allergy, and cell transplantation, thus abrogating adverse effects associated with systemic administration of immunotherapeutics. Localized immunomodulation requires con...

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Bibliographic Details
Main Authors: Simone Capuani, Nathanael Hernandez, Jesus Paez-Mayorga, Prashant Dogra, Zhihui Wang, Vittorio Cristini, Corrine Ying Xuan Chua, Joan E. Nichols, Alessandro Grattoni
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Materials Today Bio
Subjects:
Biodistribution
Drug delivery
Pharmacokinetics
PBPK
Sustained release
Cell macroencapsulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006422001880

Internet

http://www.sciencedirect.com/science/article/pii/S2590006422001880

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