Signaling and structures underpinning conducted vasodilation in human and porcine intramyocardial coronary arteries

Signaling and structures underpinning conducted vasodilation in human and porcine intramyocardial coronary arteries

BackgroundAdequate blood flow into coronary micro-arteries is essential for myocardial function. Here we assess the mechanisms responsible for amplifying blood flow into myogenically-contracting human and porcine intramyocardial micro-arteries ex vivo using endothelium-dependent and -independent vas...

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Bibliographic Details
Main Authors: Kim A. Dora, JinHeng Lin, Lyudmyla Borysova, Timea Beleznai, Michael Taggart, Raimondo Ascione, Christopher Garland
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
human coronary arterioles
coronary microvascular function
myogenic tone
Ca2+ signaling
conducted vasodilation
endothelial cell
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.980628/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.980628/full

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