mTOR signaling in proteostasis and its relevance to autism spectrum disorders

Proteins are extremely labile cellular components, especially at physiological temperatures. The appropriate regulation of protein levels, or proteostasis, is essential for all cells. In the case of highly polarized cells like neurons, proteostasis is also crucial at synapses, where quick confined c...

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Bibliographic Details
Main Authors: Judit Faus-Garriga, Isabel Novoa, Andrés Ozaita
Format: Article
Language:English
Published: AIMS Press 2017-01-01
Series:AIMS Biophysics
Subjects:
Online Access:http://www.aimspress.com/biophysics/article/1221/fulltext.html